Both adaptive and innate immune memory responses have been described in gamma delta T cells, yet the mechanisms, the ligands and the gamma delta T cell subsets generating memory responses have remain ...

Current approaches in bioengineering are synthesized and methods for their implementation are suggested for the induction and modulation of trained immunity in the treatment of human diseases.

A Bayesian decoder was employed to calculate the posterior probabilities of all position bins. This method assumes that transient counts follow a Poisson distribution and combines transient counts and ...

Diverse communities of competing species are generally characterized by substantial niche overlap and strongly stochastic dynamics. Abundance fluctuations are proportional to population size, so the ...

The fluid and the cells inside lymphatic vessels are collectively known as lymph, and although the lymphatic system extends to every part of the body, there is no central pump like the heart to keep ...

This is a well-written study that presents a solid genetic screen to identify regulators of adipose morphology and remodeling in zebrafish. The authors generated a rigorous screening platform based on ...

This valuable manuscript addresses the longstanding question of how the brain maintains serial order in working memory, proposing a biologically grounded model based on synaptic augmentation ...

eLife reviews research that gives new insights into biological molecules or uses chemical approaches to illuminate complex biological processes. Learn more about what we review and sign up for the ...

eLife reviews research spanning behavior, morphology, evolution of developmental processes, palaeontology, experimental evolution and evolutionary theory. Learn more about what we review and sign up ...

In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...

This important study uses data on over 56 million articles to examine the dynamics of interdisciplinarity and international collaborations in research journals. The data analytics used to quantify ...

Acute alcohol exposure impairs CRF-induced cholinergic activity.