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RMD Open1d
Association between glucose intolerance and psoriatic arthritis features
Patients with psoriatic arthritis (PsA) have a higher prevalence of diabetes mellitus (DM) compared to the general population ...
rmdopen.bmj2d
Single-cell RNA-sequencing analysis reveals the molecular mechanism of subchondral bone cell heterogeneity in the development of osteoarthritis - RMD Open
The cellular composition and underlying spatiotemporal transformation processes of subchondral bone in osteoarthritis (OA) remain unknown. Herein, various cell subsets from tibial plateau of patients ...
rmdopen.bmj1d
Different rheumatoid factor binding patterns distinguish between Sjögren’s disease with or without associated RA | RMD Open
Objective Rheumatoid arthritis (RA) and Sjögren’s disease (SjD) are two rheumatic autoimmune diseases that commonly co-occur. Besides some overlap in clinical presentation, the two diseases share the ...
rmdopen.bmj4d
Role of clinical and biochemical inflammation in structural progression of patients with psoriatic arthritis | RMD Open
Objective To determine the contribution of clinical and biochemical inflammation to structural progression of patients with psoriatic arthritis (PsA).Methods We analysed patients from the Infliximab ...
rmdopen.bmj7d
Guselkumab induces robust reduction in acute phase proteins and type 17 effector cytokines in active psoriatic arthritis: results from phase 3 trials - RMD Open
Objective To investigate serum protein expression in participants with psoriatic arthritis (PsA) and changes after guselkumab treatment.Methods Participants with PsA were treated with guselkumab or ...
rmdopen.bmj4d
Performance of the proposed ACR–EULAR classification criteria for systemic lupus erythematosus (SLE) in a cohort of patients with SLE with neuropsychiatric symptoms - RMD Open
Systemic lupus erythematosus (SLE) is a heterogenic connective tissue disease with a broad spectrum of clinical and laboratory manifestations. Due to this heterogeneity, SLE remains challenging to ...
rmdopen.bmj4d
Early effects of ozoralizumab 30 mg in patients with rheumatoid arthritis and inadequate response to methotrexate: a post hoc trajectory analysis of the phase II/III OHZORA ...
Objective This study assessed the early effects of ozoralizumab (OZR) 30 mg in patients with rheumatoid arthritis (RA) with inadequate response to methotrexate (MTX-IR), drawing on OHZORA trial data ...
rmdopen.bmj6d
Identifying flares in rheumatoid arthritis: reliability and construct validation of the OMERACT RA Flare Core Domain Set - RMD Open
Objective To evaluate the reliability of concurrent flare identification using 3 methods (patient, rheumatologist and Disease Activity Score (DAS)28 criteria), and construct validity of candidate ...
rmdopen.bmj12d
Predictors of response to secukinumab in patients with psoriatic arthritis and axial manifestations: a post-hoc analysis of the MAXIMISE trial | RMD Open
Results The OR (95% CI) for ASAS20 response for the presence of nail dystrophy was 3.2 (95% CI 0.93 to 10.99) in the secukinumab 150 mg group and 5.0 (95% CI 1.47 to 17.19) in the secukinumab 300 mg ...
rmdopen.bmj11d
Combination therapy of rituximab and mycophenolate in patients with systemic sclerosis and primary cardiac involvement refractory to cyclophosphamide: a retrospective ...
Despite the high mortality risk, no specific treatment options for cardiac manifestations in systemic sclerosis (SSc) currently exist. We performed a retrospective medical records analysis at our ...
rmdopen.bmj10d
Immune checkpoint inhibitors as potential triggers for ANCA vasculitis - RMD Open
Immune checkpoint inhibitors (ICIs) have made a tremendous impact on the survival of patients with certain cancers. ICIs work by interrupting co-inhibitory signalling pathways resulting in the ...