“Windows cannot access the specified device” is one of the many performance issues that League of Legends is facing after the introduction of Vanguard with patch 14.9.

If it’s a system file that is creating a problem, running the System File Checker might be a good idea. What does Windows cannot access the specified device, path or file mean?

If Windows cannot access the specified device, path or file, when trying to open Printer properties in Windows 11/10, see this post.