Here we show using a purified system that membrane targeting does not require an exposed signal-anchor sequence, as SRP-dependent targeting takes place with ribosomes containing short nascent ...

We have developed a method that detects signal sequences in cDNA fragments based on their ability to redirect a constitutively active mutant of a cytokine receptor to the cell surface, thereby ...

This article describes the ways in which protein function can be determined from DNA sequences or mRNA.

The integrative analysis of multiple data sets is becoming increasingly important in many fields of research. When the same features are studied in several independent experiments, it can often be ...

This study presents a valuable comparison of the efficiency and precision of two prime editing methods to introduce single-nucleotide variants and longer exogenous DNA sequences into the zebrafish ...