Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.

Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...

Journal of the Royal Statistical Society. Series C (Applied Statistics), Vol. 69, No. 2 (2020), pp. 301-325 (25 pages) The structure of a protein is crucial in determining its functionality and is ...

Courtesy of European Bioinformatics Institute KNOWLEDGE GAPS? Sequence alignments offer clues to both the function and evolution of novel genes. But a bewildering array of algorithms and parameters ...