Inspired by historical work showing that structure plays a role in the function of other classes of RNA such as transfer RNA, MIT biologists have now deciphered the structure of one type of lncRNA ...

As RNA shapes in individual cells can vary and drive different functions, studying the collective RNA shapes in many cells may overlook the individual variability in both RNA structure and function.

Since RNA splicing can change a protein's function, this work indicates that the structure of RNA can help control its ultimate function, which opens up a new avenue in our understanding of how the ...

Biologists have deciphered a lncRNA structure and used the information to investigate its cellular protein interactions.

Researchers at the Regensburg Center for Biochemistry (RCB) and the Regensburg Center for Ultrafast Nanoscopy (RUN) at the ...

RNA repair pathways rely on RNA ligases to maintain or manipulate RNA structure in response to biologically purposeful RNA cleavage events. The goal of this project is to illuminate the mechanisms and ...

Explore cytosine, a fundamental base in DNA and RNA, its critical role in gene regulation and epigenetics, and its significance in biotechnology and genetic diseases.

To understand the function of an RNA molecule, similar to the better-known DNA and vital for cell metabolism, we need to know its three-dimensional structure. Unfortunately, establishing the shape ...

The understanding of how RNA structure affects RNA function and the ability to engineer plant genomes at the RNA cellular level, increases the possibility of designing crop types with more ...