DNA microarray technology is one of the most important recent breakthroughs in experimental molecular biology. With evermore laboratories acquiring this high-throughput technology, the amounts of data ...

Hybridization between complementary strands of DNA enables the interrogation of unknown DNA by comparison with DNA of known sequence or genomic context. DNA microarrays containing hundreds of ...

Like it or not, biologists have to deal increasingly in informatics as their experiments generate ever larger and more complex data sets. Few laboratories have the resources to develop their own ...

Plants have a unique transdifferentiation mechanism by which differentiated cells can initiate a new program of differentiation. We used a comprehensive analysis of gene expression in an in vitro ...

The "large p, small n" paradigm arises in microarray studies, image analysis, high throughput molecular screening, astronomy, and in many other high dimensional applications. False discovery rate (FDR ...

Intense Dose-Dense Sequential Chemotherapy With Epirubicin, Paclitaxel, and Cyclophosphamide Compared With Conventionally Scheduled Chemotherapy in High-Risk Primary Breast Cancer: Mature Results of ...