Our structure, mutagenesis and nucleosome mobility shift data of the SWIRM domain define this protein module as a new chromosomal DNA–binding domain and suggest a molecular function for the ...

Growing evidence is implicating non‑B-form DNA structures in processes related to DNA stability and function, including replication and transcription. In particular, genomic studies are ...

The other side is understanding how the three-dimensional structure of different types of DNA are defined by those sequences, and, ultimately, how that defines biological function.

Explore cytosine, a fundamental base in DNA and RNA, its critical role in gene regulation and epigenetics, and its significance in biotechnology and genetic diseases.

The discovery of DNA structure by James Watson and Francis Crick in the year 1953 is one of the most revolutionary scientific discoveries to date. However, the research leading to the discovery of ...

Could DNA be glycosylated? A new study published in Engineering explores this intriguing question, suggesting that DNA might undergo glycosylation, a process that could revolutionize our understanding ...

Synthesis of 32P-Labeled DNA Chain and Its Subsequent Enzymatic Degradation by Micrococcal DNase and Calf-Spleen Phosphodiesterase to 3′ Deoxyribonucleotides (Modified from Kornberg37).

Neural networks are computing systems designed to mimic both the structure and function of the human brain. Caltech ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed.

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Scientists at Purdue University and the University of Minnesota have solved the three-dimensional structure of the central component of a biological "motor" that powers the DNA packaging system in a ...