Taking calculated risks in fantasy football drafts can often lead to a championship. Read about which risky players could help you win your 2025 league if they ball out.

The 29-year-old's combination of high rushing upside with elite-level receiving work is a match made in heaven for fantasy owners. For 2025, the answer is simple: if McCaffrey is healthy, he will be a top-five back.

Christian McCaffrey seems to be rounding back into his 2023 form, and despite the risk that comes with his injury history, he has a long runway to serve as the "centerpiece" of the 49ers' offense.

SportsLine simulated the NFL season 10,000 times and revealed its 2025 Fantasy football breakouts for 2025 Fantasy football draft prep

Discover the Fantasy Football All-Bust Team for 2025, highlighting high-ADP players like Breece Hall, Christian McCaffrey, and Travis Kelce.

NBC Sports NFL commentator Michael Holley has major concern for San Francisco 49ers over Christian McCaffrey entering 2025 season.